In the arterial disease atherosclerosis,

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Atherosclerosis is the accumulation of plaque on the interior walls of arteries, which leads to a narrowing of the arterial lumen, and thus slows blood flow. The presence of plaque also increases the risk of a thrombus (a blood clot that forms and remains in a blood vessel) or embolus (a blood clot that forms and travels to another part of the body) forming, which can further obstruct blood flow or cause other complications. Therefore, all of the above may happen in a person with atherosclerosis.

In the Arterial Disease Atherosclerosis