Substitution of which of the following groups on a cycloalkane would result in the greatest amount of steric strain?

Name: Substitution of which of the following groups on a cycloalkane would result in the greatest amount of steric strain?
Brand: Quizplus
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Question

Quizplus · Accepted Answer

The isopropyl group is larger and more bulky than both the bromo and ethyl groups, and the hydroxyl group is not bulky enough to cause significant steric strain. Therefore, substituting an isopropyl group would result in the greatest amount of steric strain.

Substitution of Which of the Following Groups on a Cycloalkane