Which of the following statements is not true regarding the conformation of substituted cyclohexanes?
A) ring flip of substituted cyclohexanes flips the axial and equatorial positions of substituents
B) substituted cyclohexanes are destabilized by 1,3-diaxial interactions
C) the twist-boat conformation of cyclohexane is more stable than the chair conformation
D) the relative amount of two conformations of substituted cyclohexanes can be determined from the difference in strain energy
Correct Answer:
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