Which of the following has a D-configuration?

Question

Quizplus · Accepted Answer

The D-configuration refers to the stereochemistry of a molecule in which the highest priority groups are arranged in a clockwise manner around the chiral center.

In option 1, the chiral center carbon has two methyl groups and two ethyl groups. If we prioritize the groups based on their atomic number, we see that the two ethyl groups are on the same side, which is an anti-clockwise direction. Therefore, this molecule does not have a D-configuration.

In option 2, the chiral center carbon has a hydrogen, a chlorine, a bromine, and a methyl group. If we prioritize the groups based on their atomic number, we see that the chlorine and the bromine are on the same side, which is a clockwise direction. Therefore, this molecule has a D-configuration.

In option 3, the chiral center carbon has a hydrogen, a chlorine, a methyl, and a phenyl group. If we prioritize the groups based on their atomic number, we see that the chlorine and the phenyl group are on the same side, which is a clockwise direction. Therefore, this molecule has a D-configuration.

Therefore, the only option with a molecule that has a D-configuration is B, which is only option 1 and 3.

Which of the Following Has a D-Configuration