Based on the following, which is true regarding the acid/base properties of guanine?
A)at physiological pH, guanine will be positively charged
B)at physiological pH, guanine will be negatively charged
C)at physiological pH, guanine will be neutral
D)at physiological pH, guanine will be a very effective buffer against base
E)at physiological pH, guanine will be a very effective buffer against acid

Question

Based on the following, which is true regarding the acid/base properties of guanine? 
A)at physiological pH, guanine will be positively charged 
B)at physiological pH, guanine will be negatively charged 
C)at physiological pH, guanine will be neutral 
D)at physiological pH, guanine will be a very effective buffer against base 
E)at physiological pH, guanine will be a very effective buffer against acid

Quizplus · Accepted Answer

Guanine is a neutral molecule at physiological pH (around 7.4). It has both acidic and basic functional groups, but these are balanced out by the pH of the surrounding solution. Therefore, at physiological pH, guanine will not be positively or negatively charged and will not act as a buffer against either acid or base.

Based on the Following, Which Is True Regarding the Acid/base