When comparing the sequences of a peripheral membrane protein with an integral membrane protein, which of the following amino acids would most likely be present in a higher percentage in the integral membrane protein?

Question

Quizplus · Accepted Answer

Integral membrane proteins are anchored to the lipids of the membrane by stretches of hydrophobic amino acids, such as leucine. Peripheral membrane proteins, on the other hand, do not penetrate the lipid bilayer and thus do not require hydrophobic amino acids to anchor them to the membrane. Therefore, leucine would be present in a higher percentage in integral membrane proteins compared to peripheral membrane proteins.

When Comparing the Sequences of a Peripheral Membrane Protein with an Integral