Assuming that gluconeogenesis was active in a mammalian liver, under what conditions would PEPCK have more activity in the mitochondria than in the cytosol?

Question

Quizplus · Accepted Answer

When lactate is the primary carbon source, pyruvate is converted to oxaloacetate in the mitochondria, and PEPCK activity is needed there to convert oxaloacetate to PEP, which can then be transported to the cytosol for gluconeogenesis.

Assuming That Gluconeogenesis Was Active in a Mammalian Liver, Under