Insulin resistance causes an increase in gluconeogenic activity in the liver due to the lack of glucose. What serves as the primary carbon source for gluconeogenesis under these conditions?

Question

Quizplus · Accepted Answer

Amino acids serve as the primary carbon source for gluconeogenesis in the liver under conditions of insulin resistance. Insulin resistance leads to decreased glucose uptake by cells, causing a lack of glucose available for gluconeogenesis. Amino acids can be converted into glucose through gluconeogenesis and serve as an important source of carbon for the liver to produce glucose.

Insulin Resistance Causes an Increase in Gluconeogenic Activity in the Liver