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Methylation of Guanine to Produce O6-Methylguanine (MG)results in What Change \rarr

Question 7

Multiple Choice

Methylation of guanine to produce O6-methylguanine (mG) results in what change to DNA?


A) mG frequently pairs with thymine resulting in a GC \rarr AT mutation
B) mG loses its methoxy group resulting in hydrogen bonding with adenine and a bulge in the double helix
C) mG is prone to deamination and eventually, depurination
D) repair of mG adducts uses a radical mechanism that has the potential to further damage adjacent bases, particularly thymine
E) none of the above

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