Which of the following S_N2 reactions is the fastest? B)CH₃CH₂CH₂I + HO^- → CH₃CH₂CH₂OH + I^- D)CH₃CH₂CH₃Br + HO^- → CH₃CH₂CH₃OH + Br^- E)CH₃CH₂CH₂I + H₂O → CH₃CH₂CH₂OH + HI

Question

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In this reaction, a nucleophilic substitution is taking place where an iodine atom is being replaced by a hydroxyl group. The reaction rate is dependent on the concentration of the reactants, the strength of the nucleophile and the leaving group. In option B, the nucleophile (HO-) is a strong base and the leaving group (I-) is a weak base. This means that I- can easily leave and be replaced by HO-. Therefore, the reaction will occur at a faster rate compared to other options.

Which of the Following SN2 Reactions Is the Fastest

Which of the Following S_N2 Reactions Is the Fastest