Which of the following statements is/are true about 5-fluorouracil,

Question

Quizplus · Accepted Answer

All of the statements are true about 5-fluorouracil. It is an anticancer drug that inhibits the enzyme thymidylate synthase, which is involved in DNA synthesis. 5-fluorouracil is an example of a mechanism-based inhibitor because it forms a covalent intermediate with the enzyme, leading to its inhibition. Additionally, it is also an example of a suicide inhibitor because it irreversibly binds to the enzyme, resulting in its destruction.

Which of the Following Statements Is/are True About 5-Fluorouracil