The first antitrust act to prohibit "conspiracies in restraint of trade" was:

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The Sherman Act, passed in 1890, was the first federal antitrust law to prohibit "conspiracies in restraint of trade" and monopolies in commerce. It remains one of the primary laws used to prevent anti-competitive behavior in the United States. The Clayton Act, passed in 1914, provided additional measures to prevent anti-competitive mergers and acquisitions. The Federal Trade Commission Act, passed in 1914, created the Federal Trade Commission to enforce antitrust laws and investigate unfair business practices. Case decisions such as those for AT&T and Microsoft are examples of how these laws are applied in specific cases, but they are not themselves antitrust acts.

The First Antitrust Act to Prohibit "Conspiracies in Restraint of Trade