In water,which form of glucose predominates?

Question

Quizplus · Accepted Answer

In water, the predominant form of glucose is the cyclic β form. This is because the hydroxyl group (-OH) on carbon 1 of glucose undergoes a reaction with the aldehyde group (-CHO) on carbon 5, forming a hemiacetal bond and creating a 6-membered cyclic structure with an oxygen atom as part of the ring. The β form is more stable than the α form due to steric hindrance between the OH group on carbon 1 and the axial position of the CH2OH group on carbon 5 in the α form. The open chain form is present in very small amounts, as it can rapidly interconvert into the cyclic forms through mutarotation.

In Water,which Form of Glucose Predominates