Which of the Following Are Assessment Features for Evaluating Patient

Which of the following are assessment features for evaluating patient response to bronchodilator therapy?
I.reversibility of airflow obstruction
II.changes in flow rates using a peak flowmeter or portable spirometry
III.changes in vital signs
IV.changes in ventilation and oxygenation
V.the patient's subjective reaction to treatment

A) II, III, and IV
B) II, III, and V
C) I, II, III, and V
D) I, II, III, IV, and V