Which of the following is a contraindication for the use of nitric oxide?

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Nitric oxide is contraindicated in patients with right-to-left shunt dependence because it can worsen their condition by increasing the amount of deoxygenated blood that bypasses the lungs and enters the systemic circulation. This can lead to systemic hypoxemia and other complications. Nitric oxide is used in the treatment of hypoxic respiratory failure, pulmonary hypertension, and in neonates older than 34 weeks with respiratory failure.

Which of the Following Is a Contraindication for the Use