The first step in the folding of disordered polypeptides into ordered functional protein is the formation of ______. A)1^o structure B)2° structure C)3° structure D)4° structure E)hydrogen bonds

Question

Quizplus · Accepted Answer

The formation of 2° structure (such as alpha helices and beta sheets) is the first step in the folding process of disordered polypeptides. This involves the formation of hydrogen bonds between carbonyl and amino groups in the polypeptide backbone, leading to a more ordered arrangement of the amino acid residues. The subsequent formation of higher-order 3° and 4° structures involves the folding of the 2° structures into a specific three-dimensional shape. The other answer choices are not accurate or complete descriptions of the folding process.

The First Step in the Folding of Disordered Polypeptides into Ordered