Avidin,a Protein Intact in Raw Egg Whites,prevents the Absorption of Biotin

Avidin,a protein intact in raw egg whites,prevents the absorption of biotin in the intestine resulting in biotin deficiency.Which of the following is affected in individuals who consume large amounts of raw egg?

A) Oxaloacetate $\to$ phosphoenolpyruvate
B) 1,3-Bisphosphoglycerate $\to$ glyceraldehyde-3-phosphate
C) Fructose-1,6-bisphosphate $\to$ fructose-6-phosphate
D) Pyruvate $\to$ oxaloacetate
E) Phosphoenolpyruvate $\to$ 2-phosphoglycerate