Which of the following is (are)characteristic of the (Na⁺-K⁺)-ATPase? (I)It binds Na⁺ and K⁺ simultaneously prior to binding ATP (II)It is covalently modified by phosphorylation at an Asp residue when Na⁺ is present. (III)Transport of Na⁺ and K⁺ occur in a 1:1 ratio,thus maintaining a balanced gradient until opening of the gated portion of the channel. (IV) It is essential for excitation of nerve cells.

Question

Quizplus · Accepted Answer

Only statement II and IV are correct. The (Na⁺-K⁺)-ATPase is covalently modified by phosphorylation at an Asp residue when Na⁺ is present. This is known as Na+/K+ ATPase pump. Also, it is essential for excitation of nerve cells. Statements I and III are incorrect as Na and K ions are transported in a 3:2 ratio and binding of Na/K ions and ATP does not happen simultaneously.

Which of the Following Is (Are)characteristic of the (Na+-K+)-ATPase

Which of the Following Is (Are)characteristic of the (Na⁺-K⁺)-ATPase