Which of the following is true about the (Na+-K+) -ATPase transporter?
A) Three potassium ions bind to the cytostolic face of the transporter in the E1 state.
B) GTP binds to it and is hydrolyzed to form GDP and a high energy phosphorylated glutamyl residue.
C) Formation of the high-energy phosphorylated glutamyl residue triggers a conformational shift from the E1 form to the E2 form.
D) Phosphate hydrolysis of the E2 state releases potassium ions to the cytosol and results in rearrangement to the E1 state.
E) All of the above correctly describe this transporter.
Correct Answer:
Verified
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