Which of the following best explains why an enzyme hasn't evolved to catalyze the following reaction as the first step of glycolysis?
glucose + P_i -> glucose-6-phosphate
I.The use of ATP is required for this step to serve as a regulatory control point.
II.The use of ATP is important because it helps keep its concentration low.Otherwise the high [ATP] would slow glycolysis too much through feedback inhibition.
III.The large positive $\Delta$ G˚' of this reaction would need to be overcome by an exceedingly high [P_i].
IV.Inorganic phosphate cannot be specifically placed on the carbon in the 6^th position.

Question

Which of the following best explains why an enzyme hasn't evolved to catalyze the following reaction as the first step of glycolysis?
glucose + P_i -> glucose-6-phosphate
I.The use of ATP is required for this step to serve as a regulatory control point.
II.The use of ATP is important because it helps keep its concentration low.Otherwise the high [ATP] would slow glycolysis too much through feedback inhibition.
III.The large positive

\Delta

G˚' of this reaction would need to be overcome by an exceedingly high [P_i].
IV.Inorganic phosphate cannot be specifically placed on the carbon in the 6^th position.

Quizplus · Accepted Answer

The Answer of Which of the following best explains why an enzyme hasn't evolved to catalyze the following reaction as the first step of glycolysis? glucose + P_i -> glucose-6-phosphate I.The use of ATP is required for this step to serve as a regulatory control point. II.The use of ATP is important because it helps keep its concentration low.Otherwise the high [ATP] would slow glycolysis too much through feedback inhibition. III.The large positive $\Delta$G˚' of this reaction would need to be overcome by an exceedingly high [P_i]. IV.Inorganic phosphate cannot be specifically placed on the carbon in the 6^th position.

Which of the Following Best Explains Why an Enzyme Hasn't Δ\DeltaΔ

Which of the Following Best Explains Why an Enzyme Hasn't $\Delta$