Which of the following best describes the structure of a nucleosome?
A)approximately 150 bp of DNA wrapped around a set of two H2A/H2B and two H3/H4 dimers with H1 on the outside
B)approximately 15 bp of DNA wrapped around an octamer of H1 with H2A,B,H3 and H4 on the outside
C)approximately 150 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside
D)approximately 1500 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside
E)approximately 200 bp of DNA wrapped around a tetramer of H2A,H2B,H3,and H4 with H1 on the outside

Question

Quizplus · Accepted Answer

A nucleosome is composed of approximately 150 base pairs (bp) of DNA wrapped around a core of eight histone proteins, which include two copies of each of the histones H2A, H2B, H3, and H4. The histone proteins and the DNA wrapped around them form a compact structure known as a nucleosome core particle. The linker DNA between nucleosomes is associated with another histone protein, H1. So, option A best describes the structure of a nucleosome.

Which of the Following Best Describes the Structure of a Nucleosome