True genetic distance may be much greater than the observed recombination frequency.Which is not an explanation of this phenomenon?
A) The genes are far apart.
B) Two crossover events may not produce recombinant chromosomes.
C) Four crossover events may not produce recombinant chromosomes.
D) Interference with 2 genes that are tightly linked affects the recombination frequency.
E) A double crossover contributes to the average number of exchanges on a chromosome.

Question

Quizplus · Accepted Answer

Interference, which is the phenomenon where one crossover event can inhibit the occurrence of another nearby crossover event, typically affects genes that are closely linked, not those that are far apart. Thus, interference would not be a reason for the true genetic distance being much greater than the observed recombination frequency, especially in the context of genes that are tightly linked. The other options (A, B, C, E) are valid explanations for why the observed recombination frequency might underestimate the true genetic distance.

True Genetic Distance May Be Much Greater Than the Observed