When John Cairns first visualized the replication of E.coli chromosomes in 1963 what did he conclude? 1.The chromosomes of E.coli are circular structures that exist as u-shaped intermediates during replication.
2)The unwinding of the two complementary parental strands and their semiconservative replication occur simultaneously or are closely coupled.
3)Semiconservative replication of the E.coli chromosome started at a specific site,and proceeded sequentially and unidirectionally around the circular structure
A) 1
B) 2
C) 3
D) 1 and 2
E) All of these

Question

Quizplus · Accepted Answer

John Cairns concluded all three statements. He visualized the replication of E.coli chromosomes and observed the circular structure of chromosomes, how the unwinding of complementary strands and their semiconservative replication occur together or closely coupled, and how the replication starts at a specific site and proceeds sequentially around the circular structure in a unidirectional manner.

When John Cairns First Visualized the Replication of E