Since the parental double helix must rotate 360° to unwind each gyre of the helix,during the semi-conservative replication of the bacterial chromosome,some kind of "swivel" must exist.What do geneticists now know that the required swivel is?
A) Topoisomerase
B) Helicase
C) A transient single-strand break produced by the action of topoisomerases
D) A transient single-strand break produced by the action of helicases
E) A transient single-strand break produced by the action of Ligase

Question

Quizplus · Accepted Answer

The required swivel is a transient single-strand break produced by the action of topoisomerases. Topoisomerases help in relieving the tension and supercoiling that occur ahead of the replication fork by creating temporary nicks in the DNA strand, allowing it to unwind properly for replication to proceed.

Since the Parental Double Helix Must Rotate 360° to Unwind