Which of the following is not a major modification that the primary transcript in eukaryotes undergoes before use during translation?
A) Methyl guanosine caps are added to the 5¢ ends of the primary transcripts
B) Poly(A) tails are added to the 3¢ ends of the transcripts
C) Intron sequences are spliced out of transcripts.
D) Exon sequences are spliced out of transcripts.
E) All of these are major modifications

Question

Quizplus · Accepted Answer

Exon sequences are not spliced out of the primary transcript during modification. Exons are the coding regions of the gene and are retained in the mature mRNA transcript. The other modifications listed, including the addition of a methyl guanosine cap, addition of a poly(A) tail, and removal of intron sequences, are all major modifications that occur during RNA processing in eukaryotes.

Which of the Following Is Not a Major Modification That