In eukaryotes,when RNA Polymerase II initiates transcription: 1.Basal transcription factors,designated TFIX (X is a letter designating individual factors),are required.
2)TFIID is the first protein to bind the promoter.
3)TFIIA catalyzes the unwinding of the DNA helix
A) 1
B) 2
C) 3
D) 1 and 2
E) All of these

Question

Quizplus · Accepted Answer

1 and 2 are correct. Basal transcription factors are indeed required for the initiation of transcription by RNA Polymerase II in eukaryotes, with TFIID being the first to bind to the promoter region, specifically recognizing the TATA box. TFIIA does not catalyze the unwinding of the DNA helix; this task is primarily accomplished by the action of RNA Polymerase II and other associated factors.

In Eukaryotes,when RNA Polymerase II Initiates Transcription: 1