During translocation the peptidyl-tRNA present in the A site of the ribosome is translocated to the P site,and the uncharged tRNA in the P site is translocated to the E site,as the ribosome moves three nucleotides toward the 3¢ end of the mRNA molecule.Which of the following soluble factors is required for this process to occur?
A) IF-1
B) EF-Tu
C) EF-G
D) IF-2
E) IF-3

Question

Quizplus · Accepted Answer

EF-G is required for translocation, as it promotes movement of the ribosome along the mRNA, allowing the peptidyl-tRNA to move from the A site to the P site, and the uncharged tRNA to move from the P site to the E site. IF-1, IF-2, and IF-3 are initiation factors, and EF-Tu is responsible for delivering aminoacyl-tRNAs to the A site during elongation, but not for translocation.

During Translocation the Peptidyl-TRNA Present in the a Site of the Ribosome