If a molecular marker such as a restriction fragment-length polymorphism (RFLP)maps close to a gene,the gene can usually be isolated by which of the following?
A) Chromosome walking
B) Chromosome jumping
C) Chromosome dancing
D) Chromosome walking and Chromosome jumping
E) All of these

Question

Quizplus · Accepted Answer

Chromosome walking and chromosome jumping can both be used to isolate the gene if the molecular marker maps close to it. Chromosome walking involves the sequential isolation of overlapping clones from a genomic library to move along the chromosome towards the gene of interest. Chromosome jumping, on the other hand, involves the isolation of a large insert clone that spans the distance between the molecular marker and the gene of interest, allowing for the direct identification of the gene. Chromosome dancing is not a valid method for isolating a gene.

If a Molecular Marker Such as a Restriction Fragment-Length Polymorphism