Somatic cell gene therapy requires a retroviral vector used.As a result,use of the therapy to treat _____ has led to leukemia.
A) Huntington's disease
B) Cystic Fibrosis
C) X-linked SCID
D) ADA-SCID
E) ALS

Question

Quizplus · Accepted Answer

Somatic cell gene therapy using retroviral vectors has been used to treat X-linked severe combined immunodeficiency (SCID), also known as "bubble boy" disease. However, in some cases, the retroviral vector used in gene therapy can insert the therapeutic gene into a site in the chromosome that activates oncogenes, leading to leukemia. This has been seen in several cases of X-linked SCID treated with gene therapy.

Somatic Cell Gene Therapy Requires a Retroviral Vector Used