Which of the following gives support to the idea that transcription takes place in "open" regions of the chromosome?
1)The fact that 3H-uridine incorporated into newly synthesized RNA is localized around the lateral loops of the lampbrush chromosomes rather than around the condensed axes in amphibian oocytes.
2)The study of polytene chromosomes in Drosophila and other Dipteran insects
3)The study of lambrush chromosomes in human oocytes
A) 1
B) 2
C) 3
D) 1 and 2
E) All of these are correct.

Question

Quizplus · Accepted Answer

Option 1 provides evidence that newly synthesized RNA is localized in the "open" regions of the chromosome because the lateral loops are regions of the chromosome that are not tightly condensed and allow for easier access for transcription machinery. Option 2 highlights the use of polytene chromosomes in studying gene expression and further supports the idea that transcription takes place in "open" regions of the chromosome. Therefore, the correct choice is D as both options support the idea that transcription occurs in open chromatin regions. Option 3 (study of lampbrush chromosomes in human oocytes) does not provide as clear evidence for open chromatin regions and can be eliminated as a choice.

Which of the Following Gives Support to the Idea That