Which of the following statements is true regarding dosage compensation?
A) In Drosophila,one of the two X-chromosomes is randomly inactivated in females.
B) In mammals,the genes on the single X-chromosome in a male are transcribed at a higher level.
C) The X-inactive specific transcript is a functional RNA molecule that results in X-inactivation in Drosophila.
D) In C.elegans,dosage compensation results from partial repression of X-linked genes in hermaphrodites.
E) The gene product of the gene maleless is responsible for X-inactivation in mammals.
Correct Answer:
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