How does p53 respond to cell stress?
1)The level of p53 increases dramatically.
2)p53 stimulates the transcription of genes whose products arrest the cell cycle.
3)p53 activates another set of genes whose products ultimately cause the damaged cell to die.

Question

Quizplus · Accepted Answer

p53 responds to cell stress by increasing its level dramatically. It then stimulates the transcription of genes whose products arrest the cell cycle to allow for DNA repair. If the damage is irreparable, p53 activates another set of genes whose products ultimately cause the damaged cell to undergo cell death (apoptosis). Therefore, all three choices (1, 2, and 3) are correct.

How Does P53 Respond to Cell Stress