Which drug administration route is most likely to result in reduced drug bioavailability?

Question

Quizplus · Accepted Answer

The enteral route involves using the GI system.Not all drugs are completely absorbed from this area,and because drugs absorbed in the GI tract first undergo some liver metabolism before entering systemic circulation (resulting in first pass loss),drugs administered enterally always have a lower bioavailability than those administered by the parenteral route.

Which Drug Administration Route Is Most Likely to Result in Reduced