Sickle-cell disease is an example of an inherited mistake in the amino acid sequence.

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Sickle-cell disease is caused by a mistake in the amino acid sequence of the beta-globin protein, which is inherited from one or both parents who have the sickle-cell trait. This mistake involves a single nucleotide change in the DNA sequence, resulting in the substitution of one amino acid (glutamic acid) with another (valine), which affects the shape and function of the protein.

Sickle-Cell Disease Is an Example of an Inherited Mistake in the Amino