Within just a few decades of Columbus's arrival in the Americas between 50 and 90 percent of the indigenous peoples of the Americas had perished from disease.

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This is a well-documented fact. The introduction of European diseases to the Americas had devastating effects on the indigenous populations, who had no immunity to the new diseases. Estimates of the death toll vary, but some scholars suggest that up to 90 percent of the native population may have died from disease in the decades following contact with Europeans.

Within Just a Few Decades of Columbus's Arrival in the Americas