This patient presents with an intraepithelial bulla from breakdown of the cellular adhesion between epithelial cells. The bulla ruptured, resulting in a painful ulcer with itching. The correct diagnosis for this progressive autoimmune disease is:

Question

This patient presents with an intraepithelial bulla from breakdown of the cellular adhesion between epithelial cells. The bulla ruptured, resulting in a painful ulcer with itching.  The correct diagnosis for this progressive autoimmune disease is:

Quizplus · Accepted Answer

The intraepithelial bulla and subsequent painful ulcer with itching are classic features of pemphigus vulgaris, an autoimmune disease characterized by the breakdown of cellular adhesion between epithelial cells. Reiter syndrome is an autoimmune disorder that primarily affects the joints, while aphthous ulcers are painful but typically smaller and do not result from an intraepithelial bulla. Langerhans cell disease is a rare disorder that affects a type of immune cell and is not associated with bulla or ulcer formation.

This Patient Presents with an Intraepithelial Bulla from Breakdown of the Cellular