A "hair-on-end" pattern may be noted on skull radiographs of a patient with:

Question

Quizplus · Accepted Answer

A "hair-on-end" pattern on skull radiographs is typically seen in patients with sickle cell anemia. This is due to the expansion of the bone marrow spaces in the skull as a compensatory mechanism for increased erythropoietic activity caused by chronic hemolysis. Polycythemia, aplastic anemia, and thalassemia do not typically present with this radiographic finding.

A "Hair-On-End" Pattern May Be Noted on Skull Radiographs of a Patient