Macrolides are antibiotics that kill bacteria by:
A)inhibiting tRNA charging.
B)releasing the protein before translation is complete.
C)blocking the exit tunnel for "empty tRNAs."
D)competing for tRNA binding in the "A site."
E)causing tRNAs to be destroyed.

Question

Quizplus · Accepted Answer

Macrolides bind to the exit tunnel of the ribosome and prevent the movement of the new protein through the tunnel. This blocks the exit tunnel for "empty tRNAs" and leads to the release of incomplete proteins, ultimately causing bacterial death.

Macrolides Are Antibiotics That Kill Bacteria By