After mutagen treatment,a molecule of 2-aminopurine (an adenine analogue)incorporates into DNA.During replication,the 2-AP protonates.The mutational event caused by this will be:
A)AT to CG.
B)GC to AT.
C)AT to TA.
D)AT to GC.
E)GC to CG.

Question

Quizplus · Accepted Answer

2-aminopurine is an analog of adenine, meaning it can base-pair with thymine (T) just like adenine. However, due to its structural differences, 2-AP can also base-pair with cytosine (C) by forming three hydrogen bonds with it instead of the usual two. During replication, when 2-AP is protonated, it will form three hydrogen bonds with guanine (G) instead of the usual two, leading to a substitution of A-T base pair with G-C base pair. Therefore, the mutational event caused by 2-AP incorporation and protonation will be AT to GC.

After Mutagen Treatment,a Molecule of 2-Aminopurine (An Adenine Analogue)incorporates into DNA.During