Which of the following mutations is/are MOST likely to result in cell overgrowth and (eventually)may lead to cancer?
A)a gain-of-function mutation in one allele of a proto-oncogene
B)a gain-of-function mutation in one allele of a tumor suppressor gene
C)a loss-of-function mutation in one allele of a proto-oncogene
D)a loss-of-function mutation in one allele of a tumor suppressor gene
E)a null mutation in one allele of a proto-oncogene

Question

Quizplus · Accepted Answer

A gain-of-function mutation in a proto-oncogene can convert it into an oncogene, leading to uncontrolled cell division and potentially cancer.

Which of the Following Mutations Is/are MOST Likely to Result