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Consider the Following Mutations And,for Each,explain Whether You Expect It

Question 45

Essay

Consider the following mutations and,for each,explain whether you expect it to be
a)potentially promoting cancer
b)dominant or recessive
i)a mutation that destroys the active site of an enzyme necessary to promote cell cycle
ii)a very premature STOP codon in a gene encoding a protein involved in the excision-repair mechanism
iii)a point mutation that renders constitutively active one of the signaling proteins in the Ras pathway
iv)a null mutation in a gene encoding an apoptotic (apoptosis-promoting)protein

Correct Answer:

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i)not cancer-promoting,probably recessiv...

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