Which of the following chromosomal aberrations can result in unmasking recessive alleles resulting in their expression?
A)deletions
B)duplications
C)inversions
D)translocations

Question

Quizplus · Accepted Answer

Deletions can lead to the loss of one copy of a gene or gene region, resulting in the unmasking of recessive alleles on the remaining copy of the chromosome. This is because a recessive allele is expressed only when the dominant allele is absent or not functioning. In the case of a deletion, the dominant allele may have been present on the lost segment of the chromosome, and the recessive allele on the remaining chromosome can now be expressed. Duplications, inversions, and translocations do not necessarily lead to the unmasking of recessive alleles.

Which of the Following Chromosomal Aberrations Can Result in Unmasking