Tay-Sachs disease is inherited as an autosomal recessive.In a certain large eastern European population,the frequency of Tay-Sachs disease is 1 percent.
a)If the population is assumed to be in Hardy-Weinberg equilibrium with respect to Tay-Sachs,what is the frequency of the allele that causes Tay-Sachs?
b)What would be the frequency of heterozygotes?
c)What is the probability of two heterozygotes marrying?
d)In children of such marriages,what would be the frequency of Tay-Sachs disease?
e)What proportion of all Tay-Sachs births are produced by such marriages?
Correct Answer:
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b)2 * 0.9 * 0.1 = 0.18
c)...
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