Which would be considered to reduce accumulation of a drug in a patient who has decreased liver function?

Question

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If a patient has decreased liver function, their ability to metabolize and eliminate drugs may be impaired. This can lead to an accumulation of the drug in the body, which can increase the risk of toxicity. To reduce this risk, the dosage may need to be reduced so that the drug can be cleared from the body more easily. Decreasing the time interval between dosages may actually increase the overall dose and exacerbate the problem. Administering the medication intravenously may also increase the risk of accumulation in a patient with decreased liver function. Changing the drug to one that has a longer half-life may also increase the risk of accumulation.

Which Would Be Considered to Reduce Accumulation of a Drug