Which statements are true regarding the pharmacologic actions of certain antidepressant drugs? (Select all that apply.)
A) MAOIs block the effects of dopamine in the central nervous system.
B) SSRIs inhibit the destruction and reuptake of serotonin at the synaptic cleft.
C) Tricyclic antidepressants block the action of norepinephrine and epinephrine in the SNS.
D) Monocyclic antidepressants such as bupropion (Wellbutrin) have an unknown mechanism of action.
E) SNRIs prolong the action of neurotransmitters by decreasing the destruction of serotonin and norepinephrine.
Correct Answer:
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