MPTP-treated primates have reduced levels of
A) acetylcholine.
B) dopamine.
C) serotonin.
D) GABA.
E) MPTP.

Question

Quizplus · Accepted Answer

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxin that selectively destroys dopaminergic neurons in the substantia nigra of the brain, leading to a reduction in dopamine levels. This is the underlying mechanism of Parkinson's disease, which is commonly modeled in primates using MPTP. The other neurotransmitters listed (acetylcholine, serotonin, and GABA) are not directly affected by MPTP toxicity.

MPTP-Treated Primates Have Reduced Levels of