A patient taking antipsychotic medication for schizophrenia is admitted with a temperature of 106 $\circ$ F. The admitting diagnosis is neuroleptic malignant syndrome secondary to antipsychotic medication. Which drug is indicated in treatment of this condition?

Question

Quizplus · Accepted Answer

Dantrolene (Dantrium) is the drug of choice in treating neuroleptic malignant syndrome (NMS). It works by blocking calcium release from the sarcoplasmic reticulum, which reduces muscular rigidity and hyperthermia associated with NMS. Edrophonium is used to diagnose myasthenia gravis, Baclofen is a muscle relaxant used in the treatment of spasticity, and Metaxolone is a muscle relaxant used in the treatment of acute musculoskeletal pain. None of these drugs are indicated in the treatment of NMS.

A Patient Taking Antipsychotic Medication for Schizophrenia Is Admitted with a Temperature