Mutations on which genes seem to be associated with early-onset Alzheimer's disease?
A)APP,PS2,and APOE
B)CLU,PICALM,and CR1
C)APP,PS1,and PS2
D)CLU,PICALM,and APOE

Question

Quizplus · Accepted Answer

Mutations in the APP, PS1, and PS2 genes have been shown to be associated with early-onset Alzheimer's disease. APOE is also a risk factor for the disease but not necessarily associated with early-onset. CLU, PICALM, and CR1 are genes that have been implicated in late-onset Alzheimer's disease.

Mutations on Which Genes Seem to Be Associated with Early-Onset