Which of the following tripeptides is formed when serine is treated with (BoC)₂O and threonine is treated with benzyl alcohol/acid first and the resulting intermediates are reacted in the presence of DCC followed by treatment with aqueous NaOH. The dipeptide is then reacted with the benzyl ester of isoleucine in the presence of DCC followed by treatment with trifluoroacetic acid and then aqueous NaOH?

Question

Quizplus · Accepted Answer

- Serine reacts with (BoC)₂O to form a serine tert-butyl ester. - Threonine reacts with benzyl alcohol/acid to form a threonine benzyl ester. - The two esters are activated with DCC and reacted to form the dipeptide Ser-Thr. - The dipeptide is then reacted with the benzyl ester of isoleucine to form the tripeptide Ser-Thr-Ile. Therefore, the correct tripeptide is Ser-Thr-Ile, and the answer is B.

Which of the Following Tripeptides Is Formed When Serine Is