On a variety of grounds, it is suspected that the memory loss that marks the earlier stages of Alzheimer's disease is associated with degenerative changes in the:
A) entorhinal cortex.
B) frontal lobes.
C) pyramidal cells of the neocortex.
D) substantia nigra.

Question

Quizplus · Accepted Answer

The entorhinal cortex is one of the first brain regions affected by Alzheimer's disease, and it plays a crucial role in memory and spatial navigation. Degenerative changes in this area are believed to be strongly associated with the memory loss seen in the early stages of the disease. The other options (frontal lobes, pyramidal cells of the neocortex, and substantia nigra) are not as strongly or consistently implicated in Alzheimer's-related memory loss.

On a Variety of Grounds, It Is Suspected That the Memory